Specialized Clinical Protocol

Living-Donor Liver Transplant (LDLT)

Life-saving surgical replacement of end-stage diseased liver using a partial graft from a healthy living family donor.

Clinical Overview

India is a preeminent global destination for LDLT, executing over 2,500 liver transplants each year with 1-year patient survival rates above 90–95%. Procedures are governed strictly by the Transplantation of Human Organs and Tissues Act (THOTA), requiring related family donors and thorough ethical committee approvals.

Conditions Commonly Evaluated

  • Decompensated Cirrhosis (Hepatitis B/C, NASH, Alcoholic, Autoimmune, Cryptogenic)
  • Hepatocellular Carcinoma (HCC) within Milan or UCSF criteria
  • Acute Liver Failure (ALF)
  • Biliary Atresia and pediatric metabolic liver diseases

Diagnostic & Workup Pathways

Surgeons and clinicians review the following diagnostic investigations to determine eligibility:

1Triple-phase Liver CT / Dynamic Liver MRI with MRCP for vascular and biliary anatomy
2Hepatic volumetric analysis for recipient-donor graft-to-recipient weight ratio (GRWR > 0.8%)
3Cardiac stress testing, pulmonary function tests, and infectious disease panel (HBV, HCV, HIV, CMV)
4Donor legal documentation and genetic/first-degree relationship verification under THOTA guidelines

Surgical Procedures & Stay Duration

Right Lobe Living-Donor Liver Transplantation

Standard procedure for adult recipients where segments V, VI, VII, VIII of donor liver are grafted.

Hospital In-Patient:14 to 21 days for recipient; 6 to 8 days for donor
Total Days in India:60 to 90 days (pre-transplant legal approval, surgery, and post-discharge stabilization)

Pediatric Left Lateral Segment Graft

Partial graft (segments II & III) transplanted to pediatric recipient with biliary atresia or genetic liver failure.

Hospital In-Patient:14 to 18 days for child; 5 to 6 days for donor
Total Days in India:45 to 60 days

Preparing for Your Specialist Consultation

Documents to Have Ready Before Consultation:

  • Comprehensive biochemical liver profile: Bilirubin, INR, Serum Albumin, Creatinine, Sodium (to calculate MELD-Na score)
  • Donor candidate details (must be medically fit relative aged 18–50, matching blood group or ABO-incompatible protocol candidate)
  • Clear digital copies of contrast-enhanced CT abdomen of recipient and prospective donor
  • Complete home country medical summary with viral markers and history of gastrointestinal bleeding or ascites

Questions You May Want to Ask Your Doctor:

  • What is the estimated MELD-Na score and urgency level for the recipient?
  • What are the statutory legal approval requirements for our specific country under Indian THOTA regulations?
  • How does your center safeguard donor safety during and following right lobe resection?
  • What is the immunosuppression monitoring protocol once we return to our home country?

Recovery & Commercial Flying Clearance

  • Recipients remain in India for a mandatory 6 to 8 weeks post-discharge for weekly liver function and tacrolimus trough level checks
  • Donors regenerate ~85–90% of their liver volume within 6 to 8 weeks and can usually fly home within 3 to 4 weeks
  • CareBridge India coordinates specialized hygienic serviced apartments with private kitchen facilities to protect immunosuppressed recipients
Pricing GuidanceDirect Hospital Billing

Living-donor liver transplant packages in India typically range from $28,000 to $42,000 USD (inclusive of recipient and donor surgery, ICU stay, and initial medications), compared to $400,000 to $800,000 USD in North America and Western Europe.

Source: National Organ and Tissue Transplant Organisation (NOTTO) & Directorate General of Health Services (Verified: 2025-07-20)

Medical Disclaimer

This content is educational and for preliminary planning purposes. It does not replace individualized clinical assessment by a licensed physician. Treatment suitability is established only after comprehensive diagnostic examination.